Since January 2022, the 11th version of the International Classification of Diseases (ICD-11) came into effect. It includes a new classification system for chronic pain, which could change how chronic pain is perceived, diagnosed, managed, and paid for. We will present and discuss the potential impact of the new classification on pediatric chronic pain in an interactive session with the audience. Dr. Jeremy Gauntlett-Gilbert reviews how chronic primary pain diagnoses may affect the culture of acute medicine, stigma, and help to address parent fears and coping. Dr. See Wan Tham will illustrate the clinical perspective on how application of the ICD-11 diagnoses could influence conceptualization of pain diagnoses from the perspective of patients and families, treatment options, and comparison to other diagnostic classification systems. Dr. Christine Greco will provide insight on the implications of a new diagnostic system on healthcare financial resources and reimbursements on medical institutions and patients and families. She will propose strategies how we can advocate for continued and adequate health care coverage for treatment of chronic pain in children and adolescents in the future. Lisa-Marie Rau will outline a data-informed approach to evaluate chronic pain diagnostic criteria with the goal of enhancing the utility of ICD-11 for the pediatric population.